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Elizabeth Gifford: The Life and Times

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Senior Honors Thesis

A Multifaceted Interactive Analysis of the Behavior of a Single Neuron Model

Elizabeth A. Gifford
Brandeis University, Department of Computer Science
Senior Honors Thesis, May 2006

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Introduction

In the course of my research, I developed several techniques to explore the contents of a large database of the various activity patterns of a single neuron model. I used feature extraction and k-means clustering to assign attributes to neuron models that could vary as the modeľs inputs vary and developed a visualization software tool to facilitate the exploration of that relationship.

Other Contents

Biological Background
Creating the Data Set
Computational Goals
Software Design
Compression
Human Classification Tool
Feature Extraction
Two-Dimensional Slice Viewer
Mining Activity Patterns Using K-Means Clustering
Conclusion
Future Work